Cancer Immunotherapy
Dow, Wotman, Boss, Martin, Regan, McGrath
- Immune modulation of the tumor microenvironment using repurposed drugs targeting myeloid cells for bone cancer and brain cancer in dogs and humans.
- B7-H3 CAR T cells for treatment of bone cancer and brain cancer in dogs and humans.
- Intratumor immunotherapy for ocular surface neoplasia and genital squamous cell carcinoma in horses.
- Intratumoral immunotherapy for squamous cell carcinoma in cats.
- Oral immunotherapy for GI lymphoma in cats.
Immunity in Osteoarthritis and Musculoskeletal Diseases
Pezzanite, Goodrich, Easley
- Joint immunity in osteoarthritis in horse and mouse models.
- Cellular therapy to treat infections and stimulate joint health.
Non-Invasive GI Diagnostic Technologies
Manchester, Lappin
- Gene profiling in inflammatory bowel disease in dogs and cats using stool specimens.
Airway Immunity in Cattle
Raabis
- Analysis of airway immune responses in healthy and stressed cattle.
Topical Drug Delivery Technologies for Wound Care and Ocular Care
McGilvray, Pezzanite, Lappin
- Evaluation of VitalFoam technologies in animal models and clinical trials.
- Evaluation of Ocummune eye drops for chronic herpesvirus infection in cats.