Research Projects

Immunotherapy Research Laboratory

Cancer Immunotherapy

Dow, Wotman, Boss, Martin, Regan, McGrath

  • Immune modulation of the tumor microenvironment using repurposed drugs targeting myeloid cells for bone cancer and brain cancer in dogs and humans.
  • B7-H3 CAR T cells for treatment of bone cancer and brain cancer in dogs and humans.
  • Intratumor immunotherapy for ocular surface neoplasia and genital squamous cell carcinoma in horses.
  • Intratumoral immunotherapy for squamous cell carcinoma in cats.
  • Oral immunotherapy for GI lymphoma in cats.

Immunity in Osteoarthritis and Musculoskeletal Diseases

Pezzanite, Goodrich, Easley

  • Joint immunity in osteoarthritis in horse and mouse models.
  • Cellular therapy to treat infections and stimulate joint health.

Non-Invasive GI Diagnostic Technologies

Manchester, Lappin

  • Gene profiling in inflammatory bowel disease in dogs and cats using stool specimens.

Airway Immunity in Cattle

Raabis

  • Analysis of airway immune responses in healthy and stressed cattle.

Topical Drug Delivery Technologies for Wound Care and Ocular Care

McGilvray, Pezzanite, Lappin

  • Evaluation of VitalFoam technologies in animal models and clinical trials.
  • Evaluation of Ocummune eye drops for chronic herpesvirus infection in cats.