Kading Lab

Our lab, of the Center for Vector-Borne Infectious Diseases (CVID), studies the ecology and transmission dynamics of vector-borne pathogens, particularly emerging arboviruses. A multitude of factors influence the enzootic circulation of arboviruses and their potential for introduction and establishment in new geographic areas. We are interested in understanding the natural, sylvatic circulation of arboviruses in endemic areas, how an arbovirus might become established in vector and host populations in new geographic areas, and entomological risk factors surrounding such introductions.

To this end, our field and laboratory studies are focused on evaluation of the biological capacity of different mosquito species and populations to support virus replication and serve as efficient vectors, potential mechanisms for virus maintenance in mosquito populations, and the how the interactions of a mosquito species with competent vertebrate amplifying hosts over space and time may influence epizootic virus activity. In addition to these entomological studies, we have an ongoing project to investigate the potential role of bats as arbovirus reservoirs and a source of emerging arboviruses. The Kading lab is also a part of the Rockies and High Plains Vector-borne Diseases Center, a regional training and evaluation center funded by the CDC

research project

Potential of North American mosquitoes to transmit and maintain Rift Valley fever virus (RVFV)

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research project

Ecology, Epidemiology, and Biosurveillance for emerging viral pathogens of Ugandan bats

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research project

Surveillance of Mosquito and Arbovirus Dispersal Using Smart Microcrystals

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research project

Transstadial inhibition of Rift Valley Fever virus infection in Ae. aegypti mosquitoes

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Publications

Rift Valley Fever Virus Transmission During an Unreported Outbreak Among People and Livestock in South-Central Tanzania. Viruses.
Sumaye RD, Brandão APD, Chilanga F, Paul G, Mwangoka GW, Smith WA, Ekiri AB, Kilonzo C, Mwakasungula S, Makingi G, Kinyogori AA, Magesa WS, Samson AJ, Mkindi C, Pazia P, Hassan F, Mbaga TA, Mdegela RH, Masanja H, Cannon D, Gibbons A, Klena JD, Montgomery JM, Nichol ST, Jurisic L, Tremeau-Bravard A, Nonga H, Sebastian J, Zewdie S, Streb L, Fagre AC, Bergren NA, Hartman DA, Wolking DJ, Kading RC, Mazet JAK, Bird BH. 2025 Sep 30;17(10):1329. doi: 10.3390/v17101329. PMID: 41157601; PMCID: PMC12567855.

A minimum data standard for wildlife disease research and surveillance.
Schwantes CJ, Sánchez CA, Stevens T, Zimmerman R, Albery G, Becker DJ, Brookson CB, Kading RC, Keiser CN, Khandelwal S, Kramer-Schadt S, Krut-Landau R, McKee C, Montecino-Latorre D, O’Donoghue Z, Olson SH, O’Shea M, Poisot T, Robertson H, Ryan SJ, Seifert SN, Simons D, Vicente-Santos A, Wood CL, Graeden E, Carlson CJ. Sci Data. 2025 Jun 21;12(1):1054. doi: 10.1038/s41597-025-05332-x. PMID: 40544158 Free PMC article.

The Temperature-Associated Effects of Rift Valley Fever Virus Infections in Mosquitoes and Climate-Driven Epidemics: A Review
Azerigyik FA, Cagle SM, Wilson WC, Mitzel DN, Kading RC. Viruses. 2025 Feb 1;17(2):217. doi: 10.3390/v17020217. PMID: 40006972

Intrinsic factors driving mosquito vector competence and viral evolution: a review.
Lewis J, Gallichotte EN, Randall J, Glass A, Foy BD, Ebel GD, Kading RC. Front Cell Infect Microbiol. 2023 Dec 21;13:1330600. doi: 10.3389/fcimb.2023.1330600. eCollection 2023. PMID: 38188633

On the origin and evolution of the mosquito male-determining factor Nix.
Biedler JK, Aryan A, Qi Y, Wang A, Martinson EO, Hartman DA, Yang F, Sharma A, Morton KS, Potters M, Chen C, Dobson SL, Ebel GD, Kading RC, Paulson S, Xue RD, Strand MR, Tu Z. Mol Biol Evol. 2023 Dec 21:msad276. doi: 10.1093/molbev/msad276. Online ahead of print.PMID: 38128148

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People

Rebekah Kading
Rebekah Kading, Ph.D.

Lab Principal Investigator [PI]
Assistant Professor

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