Kading Lab

Our lab, of the Center for Vector-Borne Infectious Diseases (CVID), studies the ecology and transmission dynamics of vector-borne pathogens, particularly emerging arboviruses. A multitude of factors influence the enzootic circulation of arboviruses and their potential for introduction and establishment in new geographic areas. We are interested in understanding the natural, sylvatic circulation of arboviruses in endemic areas, how an arbovirus might become established in vector and host populations in new geographic areas, and entomological risk factors surrounding such introductions.

To this end, our field and laboratory studies are focused on evaluation of the biological capacity of different mosquito species and populations to support virus replication and serve as efficient vectors, potential mechanisms for virus maintenance in mosquito populations, and the how the interactions of a mosquito species with competent vertebrate amplifying hosts over space and time may influence epizootic virus activity. In addition to these entomological studies, we have an ongoing project to investigate the potential role of bats as arbovirus reservoirs and a source of emerging arboviruses.

research project

Potential of North American mosquitoes to transmit and maintain Rift Valley fever virus (RVFV)

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research project

Ecology, Epidemiology, and Biosurveillance for emerging viral pathogens of Ugandan bats

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research project

Surveillance of Mosquito and Arbovirus Dispersal Using Smart Microcrystals

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research project

Transstadial inhibition of Rift Valley Fever virus infection in Ae. aegypti mosquitoes

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Exploring the Mosquito-Arbovirus Network: A Survey of Vector Competence Experiments.
Chen B, Sweeny AR, Wu VY, Christofferson RC, Ebel G, Fagre AC, Gallichotte E, Kading RC, Ryan SJ, Carlson CJ.Am J Trop Med Hyg. 2023 Apr 10;108(5):987-994. doi: 10.4269/ajtmh.22-0511. Print 2023 May 3. PMID: 37037424

Scalable Combinatorial Assembly of Synthetic DNA for Tracking Applications.
Stuart JD, Wickenkamp NR, Davis KA, Meyer C, Kading RC, Snow CD.Int J Mol Sci. 2023 Jan 29;24(3):2549. doi: 10.3390/ijms24032549. PMID: 36768872

Mosquito tagging using DNA-barcoded nanoporous protein microcrystals.
Stuart JD, Hartman DA, Gray LI, Jones AA, Wickenkamp NR, Hirt C, Safira A, Regas AR, Kondash TM, Yates ML, Driga S, Snow CD, Kading RC. PNAS Nexus. 2022 Sep 12;1(4):pgac190. doi: 10.1093/pnasnexus/pgac190. eCollection 2022 Sep. PMID: 36714845

Exposure of Egyptian Rousette Bats (Rousettus aegyptiacus) and a Little Free-Tailed Bat (Chaerephon pumilus) to Alphaviruses in Uganda.
Kading RC, Borland EM, Mossel EC, Nakayiki T, Nalikka B, Ledermann JP, Crabtree MB, Panella NA, Nyakarahuka L, Gilbert AT, Kerbis-Peterhans JC, Towner JS, Amman BR, Sealy TK, Miller BR, Lutwama JJ, Kityo RM, Powers AM.Diseases. 2022 Dec 5;10(4):121. doi: 10.3390/diseases10040121. PMID: 36547207

A Novel Glucocorticoid and Androgen Receptor Modulator Reduces Viral Entry and Innate Immune Inflammatory Responses in the Syrian Hamster Model of SARS-CoV-2 Infection.
Rocha SM, Fagre AC, Latham AS, Cummings JE, Aboellail TA, Reigan P, Aldaz DA, McDermott CP, Popichak KA, Kading RC, Schountz T, Theise ND, Slayden RA, Tjalkens RB.Front Immunol. 2022 Feb 16;13:811430. doi: 10.3389/fimmu.2022.811430. eCollection 2022. PMID: 35250984

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Rebekah Kading, Ph.D.

Lab Principal Investigator [PI]
Assistant Professor

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