The Goodrich Lab research projects are focused on treating and preventing disease transmission. This includes research on methods to prevent transfusion transmitted diseases by using photochemical methods to inactivate bacteria, viruses and parasites that may be transmitted in donated blood products. The work in the Goodrich Lab and through collaborations with other investigators has led to the development of several vaccine candidates for diseases including SARS-CoV-2, Tuberculosis, Human and Avian Influenza and African Swine Fever, using a technology platform for production of vaccines and treatment of blood products invented in collaboration with colleagues at Colorado State University.
Publications
Kaposi’s sarcoma herpesvirus seroprevalence among blood donors in Uganda
Huso T, White JL, Kyeyune D, D’Adamo A, Labo N, Miley W, et al. Transfusion. 2025. https://doi.org/10.1111/trf.18236
Emerging Pathogen Threats in Transfusion Medicine: Improving Safety and Confidence with Pathogen Reduction Technologies
Cardoso M, Ragan I, Hartson L, Goodrich RP. Pathogens. 2023 Jul 5;12(7):911. doi: 10.3390/pathogens12070911. PMID: 37513758
SARS-CoV-2 seroprevalence among blood donors in Uganda: 2019-2022.
Bloch EM, Kyeyune D, White JL, Ddungu H, Ashokkumar S, Habtehyimer F, Baker O, Kasirye R, Patel EU, Grabowski MK, Musisi E, Moses K, Hume HA, Lubega I, Shrestha R, Motevalli M, Fernandez RE, Reynolds SJ, Redd AD, Wambongo Musana H, Dhabangi A, Ouma J, Eroju P, de Lange T, Fowler MG, Musoke P, Stramer SL, Whitby D, Zimmerman PA, McCullough J, Sachithanandham J, Pekosz A, Goodrich R, Quinn TC, Ness PM, Laeyendecker O, Tobian AAR. Transfusion. 2023 Jul;63(7):1354-1365. doi: 10.1111/trf.17449. Epub 2023 Jun 16. PMID: 37255467
Pathogen reduction of monkeypox virus in plasma and whole blood using riboflavin and UV light.
Izabela K Ragan, Lindsay M Hartson, Elizabeth J Sullivan, Richard A Bowen, Raymond P Goodrich (2023) PLoS One 18 (1), e0278862
The Mirasol Evaluation of Reduction in Infections Trial (MERIT) : study protocol for a randomized controlled clinical trial.
Aaron Tobian; Ronnnie Kasirye; Heather Hume; Evan Bloch; Irene Lubega; Dorothy Kyeyune; Ruchee Shrestha; Henry Ddungu; Hellen Wambongo Musana; Aggrey Dhabangi; Joseph Ouma; Priscilla Eroju; Telsa de Lange; Michael Tartakovsky; Jodie White; Ceasar Kakura; Mary Glenn Fowler; Philippa Musoke; Monica Nolan; Kate Grabowski; Lawrence Moulton; Susan Stramer; Denise Whitby; Peter Zimmerman; Deo Wabwire; Isaac Kajja; Jeffrey McCullough; Raymond Goodrich; Thomas Quinn; Robert Cortes; Paul Ness (2022) 23(1): 1-13.
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