The Foy lab is conducting a field study that will test a new method to control the transmission of West Nile Virus around Northern Colorado households. Interested in participating? Check out this flyer for more information.
As a member of the Center for Vector-Borne Infectious Diseases (CVID) at Colorado State University, the Foy laboratory focuses on the interactions of vectors with their hosts and with vector pathogens. The goal is to link research employing molecular, proteomic and genomic techniques to practical applications for controlling arthropod-borne diseases. A main research component in the Foy lab is to interrupt the intense transmission of malaria and arboviruses by targeting the vector through their bloodmeals using drugs that attack vector physiology and that inhibit pathogen development or using anti-vector immunity driven by vaccination. The Foy lab is also developing mosquitoes and other vectors as biosurveillance tools, studying unique aspects of arbovirus transmission and arbovirus survival in vectors, and studying poorly understood mosquito pathogens for their prospects to become vector-borne disease control tools. The Foy lab is also a part of the Rockies and High Plains Vector-borne Diseases Center, a regional training and evaluation center funded by the CDC where Brian Foy serves as co-director.
research project
Repeat Ivermectin Mass Drug Administrations for Malaria control II (RIMDAMAL II)
This is a cluster randomized clinical trial in Burkina Faso to test whether repeated ivermectin mass drug administrations, integrated into a monthly delivery platform with standard malaria control measures of seasonal malaria chemoprevention and insecticide-treated bed net distribution, will reduce childhood malaria incidence and limit resistance development in mosquitoes and parasites.
research project
TRANSMIT: Tracking Antimalarial Resistance in Mosquito Populations
This project is designed to compare malaria parasite drug resistance tracking techniques using human blood samples versus using captured blood fed mosquito samples.
research project
Comparison of mosquito age-grading measures in the RIMDAMAL II randomized, double-blind clinical trial
This project is comparing new and old mosquito age grading techniques within the context of our RIMDAMAL II clinical trial to best determine how different vector-control measures mosquito population age structure.
research project
Aedes-borne arbovirus transmission
We are studying humans and animal models to characterize the viral dynamics, host responses and disease outcomes resulting from Aedes-borne arbovirus transmission. We are especially interested in understanding these outcomes from Zika virus transmission by the sexual and mosquito-borne routes. Our human studies partners are researchers at FIOCRUZ, Aggeu Magalhaes Institute, Recife, PE, Brazil.
research project
Endectocides for West Nile virus control
This project designed to develop and test endectocide-treated bird feed for efficacy in controlling West Nile virus transmission. Our partners are colleagues at UC-Davis, CDC-DVBD, and TDA Research, Inc.
Publications
Intrinsic factors driving mosquito vector competence and viral evolution: a review.
Lewis J, Gallichotte EN, Randall J, Glass A, Foy BD, Ebel GD, Kading RC. Front Cell Infect Microbiol. 2023 Dec 21;13:1330600. doi: 10.3389/fcimb.2023.1330600. eCollection 2023. PMID: 38188633
Evaluation of Vector-Enabled Xenosurveillance in Rural Guatemala.
McMinn RJ, Chacon A, Rückert C, Scorza V, Young MC, Worthington D, Lamb MM, Medrano RE, Harris EK, Arias K, Lopez MR, Asturias EJ, Foy BD, Stenglein MD, Olson D, Ebel GD. Am J Trop Med Hyg. 2023 Oct 16;109(6):1303-1310. doi: 10.4269/ajtmh.22-0774. Print 2023 Dec 6. PMID: 37972312
Colorado tick fever virus: a review of historical literature and research emphasis for a modern era.
Harris EK, Foy BD, Ebel GD. J Med Entomol. 2023 Oct 20:tjad094. doi: 10.1093/jme/tjad094. Online ahead of print. PMID: 37862094
Predicted reduction in transmission from deployment of ivermectin-treated birdfeeders for local control of West Nile virus.
Holcomb KM, Nguyen C, Komar N, Foy BD, Panella NA, Baskett ML, Barker CM. Epidemics. 2023 Sep;44:100697. doi: 10.1016/j.epidem.2023.100697. Epub 2023 Jun 16. PMID: 37348378
Tracking antimalarial drug resistance using mosquito blood meals: a cross-sectional study.
Ehrlich HY, Somé AF, Bazié T, Ebou CN, Dembélé EL, Balma R, Goodwin J, Wade M, Bei AK, Ouédraogo JB, Foy BD, Dabiré RK, Parikh S. Lancet Microbe. 2023 Apr 19:S2666-5247(23)00063-0. doi: 10.1016/S2666-5247(23)00063-0. Online ahead of print. PMID: 37086737
more publications
People
Brian Foy, Ph.D.
Lab Principal Investigator [PI]
Co-Director of Rockies and High Plains Vector-Born Infecious Diseases Center
Professor
Chilinh Nguyen and Brian Foy building field study boxes.
Soleil Foy and Jasmine Donkoh in the insectary.
Erin Markle presenting her undergraduate research.
Members of the Foy lab participated in a local March for Science.
contact information
Office: Center for Vector-Borne Infectious Diseases room 168
(970) 491-3470
[email protected]