Repeat Ivermectin Mass Drug Administrations for Malaria control II (RIMDAMAL II)
This is a cluster randomized clinical trial in Burkina Faso to test whether repeated ivermectin mass drug administrations, integrated into a monthly delivery platform with standard malaria control measures of seasonal malaria chemoprevention and insecticide-treated bed net distribution, will reduce childhood malaria incidence and limit resistance development in mosquitoes and parasites.
TRANSMIT: Tracking Antimalarial Resistance in Mosquito Populations
This project is designed to compare malaria parasite drug resistance tracking techniques using human blood samples versus using captured blood fed mosquito samples.
Comparison of mosquito age-grading measures in the RIMDAMAL II randomized, double-blind clinical trial
This project is comparing new and old mosquito age grading techniques within the context of our RIMDAMAL II clinical trial to best determine how different vector-control measures mosquito population age structure.
Aedes-borne arbovirus transmission
We are studying humans and animal models to characterize the viral dynamics, host responses and disease outcomes resulting from Aedes-borne arbovirus transmission. We are especially interested in understanding these outcomes from Zika virus transmission by the sexual and mosquito-borne routes. Our human studies partners are researchers at FIOCRUZ, Aggeu Magalhaes Institute, Recife, PE, Brazil.
Endectocides for West Nile virus control
This project designed to develop and test endectocide-treated bird feed for efficacy in controlling West Nile virus transmission. Our partners are colleagues at UC-Davis, CDC-DVBD, and TDA Research, Inc.
Ivermectin as a novel complementary malaria control tool to reduce incidence and prevalence: a modelling study.
Slater HC, Foy BD, Kobylinski K, Chaccour C, Watson OJ, Hellewell J, Aljayyoussi G, Bousema T, Burrows J, D’Alessandro U, Alout H, Ter Kuile FO, Walker PGT, Ghani AC, Smit MR.
Lancet Infect Dis. 2020 Jan 13. pii: S1473-3099(19)30633-4. doi: 10.1016/S1473-3099(19)30633-4. [Epub ahead of print]
Successive blood meals enhance virus dissemination within mosquitoes and increase transmission potential.
Armstrong PM, Ehrlich HY, Magalhaes T, Miller MR, Conway PJ, Bransfield A, Misencik MJ, Gloria-Soria A, Warren JL, Andreadis TG, Shepard JJ, Foy BD, Pitzer VE, Brackney DE.
Nat Microbiol. 2020 Feb;5(2):239-247. doi: 10.1038/s41564-019-0619-y. Epub 2019 Dec 9.
Induction of RNA interference to block Zika virus replication and transmission in the mosquito Aedes aegypti.
Magalhaes T, Bergren NA, Bennett SL, Borland EM, Hartman DA, Lymperopoulos K, Sayre R, Borlee BR, Campbell CL, Foy BD, Olson KE, Blair CD, Black W 4th, Kading RC.
Insect Biochem Mol Biol. 2019 Aug;111:103169. doi: 10.1016/j.ibmb.2019.05.004. Epub 2019 May 17.
Efficacy and risk of harms of repeat ivermectin mass drug administrations for control of malaria (RIMDAMAL): a cluster-randomised trial.
Foy BD, Alout H, Seaman JA, Rao S, Magalhaes T, Wade M, Parikh S, Soma DD, Sagna AB, Fournet F, Slater HC, Bougma R, Drabo F, Diabaté A, Coulidiaty AGV, Rouamba N, Dabiré RK.
Lancet. 2019 Apr 13;393(10180):1517-1526. doi: 10.1016/S0140-6736(18)32321-3. Epub 2019 Mar 14.
Evaluation of a novel West Nile virus transmission control strategy that targets Culex tarsalis with endectocide-containing blood meals.
Nguyen C, Gray M, Burton TA, Foy SL, Foster JR, Gendernalik AL, Rückert C, Alout H, Young MC, Boze B, Ebel GD, Clapsaddle B, Foy BD.
PLoS Negl Trop Dis. 2019 Mar 7;13(3):e0007210. doi: 10.1371/journal.pntd.0007210. eCollection 2019 Mar.
Lab Principal Investigator [PI]
Research Scientist/Scholar II
Research Associate I
Graduate Research Assistant
Graduate Research Assistant
Soleil Foy and Jasmine Donkoh in the insectary.
Erin Markle presenting her undergraduate research.
Members of the Foy lab participated in a local March for Science.
Chilinh Nguyen and Brian Foy building field study boxes.
news and updates
An international team led by CSU Professor Brian Foy found that they were able to reduce cases of malaria in children in several villages in Burkina Faso by 20 percent, using a drug called ivermectin.
Brian Foy explains the scientific aims of a recent international study in Burkina Faso to reduce malaria transmission using a drug called ivermectin.
To prove that mosquitoes were ‘living syringes’ for infectious disease, Brian Foy’s lab conducted field work in Liberia, collecting & dissecting mosquitoes to track the diseases they carried.
Office: Arthropod-borne and Infectious Diseases Laboratory room 112