Jeff Wilusz Lab

​​​​​​​The Jeffrey Wilusz lab is interested in the mechanisms and regulation of mRNA metabolism in eukaryotic cells and how these processes influence pathogenesis of human diseases, including cancer, viral infection and myotonic dystrophy. We are also examining how mRNA decay contributes to the achievement and maintenance of pluripotency in stem cells.​ 

research project

Research Focus Area or Project

Publications

EBV-Induced LINC00944: A Driver of Oral Cancer Progression and Influencer of Macrophage Differentiation.
Srisathaporn S, Ekalaksananan T, Heawchaiyaphum C, Aromseree S, Maranon DG, Altina NH, Nukpook T, Wilusz J, Pientong C. Cancers (Basel). 2025 Feb 1;17(3):491. doi: 10.3390/cancers17030491. PMID: 39941858

UV damage induces production of mitochondrial DNA fragments with specific length profiles.
Waneka G, Stewart J, Anderson JR, Li W, Wilusz J, Argueso JL, Sloan DB. bioRxiv. 2023 Nov 11:2023.11.07.566130. doi: 10.1101/2023.11.07.566130. Preprint.PMID: 37986892

Dynamic “Cap”-abilities of P-bodies and the XRN1-EDC4 axis.
Malsick LE, Wilusz J. EMBO J. 2023 Nov 2;42(21):e115310. doi: 10.15252/embj.2023115310. Epub 2023 Sep 26. PMID: 37750488

A plant-infecting subviral RNA associated with poleroviruses produces a subgenomic RNA which resists exonuclease XRN1 in vitro.
Campbell AJ, Anderson JR, Wilusz J. Virology. 2022 Jan;566:1-8. doi: 10.1016/j.virol.2021.11.002. Epub 2021 Nov 17.PMID: 34808564

Aedes aegypti miRNA-33 modulates permethrin induced toxicity by regulating VGSC transcripts.
Kubik TD, Snell TK, Saavedra-Rodriguez K, Wilusz J, Anderson JR, Lozano-Fuentes S, Black WC 4th, Campbell CL. Sci Rep. 2021 Mar 31;11(1):7301. doi: 10.1038/s41598-021-86665-6.

more publications

People

Jeff Wilusz
Jeff Wilusz, Ph.D.

Lab Principal Investigator [PI]
Professor
Director, Online Microbiology-Immunology Masters Program

news and updates view all

April 17, 2024 MIP professor honored with inaugural CSU Board of Governors Excellence in Graduate Teaching Award

A proven leader in research and education, Jeffrey Wilusz has been selected as the first ever recipient of the CSU Board of Governors Excellence in Graduate Teaching award.
May 4, 2020 College faculty, staff honored virtually for Celebrate! CSU 2020

Jeff Wilusz was awarded the 2020 Oliver P. Pennock Distinguished Service Award, which recognizes meritorious and outstanding achievement in the last five years.

contact information

Office: Microbiology Room C330

Lab: Microbiology Room B325

(970) 491-4881