Santangelo Research Team

The mission of the Kelly Santangelo research team is to enhance healthspan throughout lifespan by aiding and abetting functional, independent, and/or pain-free mobility.

The Santangelo research team is a part of the:

research project

Translational Research

Enhance healthspan throughout lifespan by aiding and abetting functional, independent, and/or pain-free mobility.

research project

Clinical Research

Improve the diagnostic quality (accuracy, sensitivity, specificity and positive/negative predictive values) of antemortem testing for feline infectious peritonitis (FIP), while maintaining low cost, minimally invasive and clinically applicable qualities.


Systemic administration of a pharmacologic iron chelator reduces cartilage lesion development in the Dunkin-Hartley model of primary osteoarthritis.

Burton LH, Afzali MF, Radakovich LB, Campbell MA, Culver LA, Olver CS, Santangelo KS.
Free Radic Biol Med. 2021 Dec 16;179:47-58. doi: 10.1016/j.freeradbiomed.2021.12.257. Online ahead of print. PMID: 34923104

Plasma and joint tissue pharmacokinetics of two doses of oral cannabidiol oil in guinea pigs (Cavia porcellus).

Spittler AP, Helbling JE, McGrath S, Gustafson DL, Santangelo KS, Sadar MJ.
J Vet Pharmacol Ther. 2021 Nov;44(6):967-974. doi: 10.1111/jvp.13026. Epub 2021 Oct 17. PMID: 34658021

Age- and sex-associated differences in hematology and biochemistry parameters of Dunkin Hartley guinea pigs (Cavia porcellus).

Spittler AP, Afzali MF, Bork SB, Burton LH, Radakovich LB, Seebart CA, Moore AR, Santangelo KS.
PLoS One. 2021 Jul 9;16(7):e0253794. doi: 10.1371/journal.pone.0253794. eCollection 2021. PMID: 34242236

Evaluation of electroacupuncture for symptom modification in a rodent model of spontaneous osteoarthritis.

Spittler AP, Afzali MF, Martinez RB, Culver LA, Leavell SE, Timkovich AE, Sanford JL, Story MR, Santangelo KS.
Acupunct Med. 2021 Dec;39(6):700-707. doi: 10.1177/09645284211020755. Epub 2021 Jun 9. PMID: 34105396

Multiplex fluorescent immunocytochemistry for the diagnosis of feline infectious peritonitis: Determining optimal storage conditions.

Howell M, Evans SJM, Cornwall M, Santangelo KS.
Vet Clin Pathol. 2020 Dec;49(4):640-645. doi: 10.1111/vcp.12912. Epub 2021 Jan 5. PMID: 33403708

more publications


Kelly Santangelo, D.V.M., Ph.D., D.A.C.V.P.

Lab Principal Investigator [PI]
Associate Professor

Mary Afzali, Ph.D.

Research Scientist II

Lindsey Burton, Ph.D.

Postdoctoral Fellow

Joel Helbling, D.V.M.

Postdoctoral Fellow
Comparative Medicine Resident

Heidi Kloser

Graduate Research Assistant

Ariel Timkovich

Graduate Research Assistant

Cassie Seebart

DVM Student Researcher

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