VandeWoude Lab

The VandeWoude Laboratory studies a variety of agents that infect domestic and nondomestic cats, most predominantly Feline Immunodeficiency Virus.

The mission of the VandeWoude Lab is to:

  • Train undergraduate, graduate, pre- and post-DVM students, and post-doctoral fellows in modern techniques in molecular virology, with emphasis on experimental design, data interpretation, and accurate and fluent reporting of results.
  • Strive to continuously develop new methodologies to apply to the research process.
  • Facilitate productive and collaborative interactions between SVRG lab members and collaborators both internal and external to CSU.
  • Extrapolate findings to whole animal and population health, in vivo relevance, and community/ecological impacts.
  • Challenge existing dogma with an open mind and thoughtful approach.
  • Generate enthusiasm and appreciation for the impact of well-considered scientific approaches on human and animal health and well-being.
  • Provide a supportive, lively, challenging, cooperative and fun environment for scientific investigations in complementary disciplines.

VandeWoude Lab Research Aims

research project

Feline Ecology: Landscapes, Infectious Disease, And Epidemics

There are many questions about the spread of disease in felines. The FELIDAE (Feline Ecology: Landscapes, Infectious Disease, And Epidemics) research project seeks to answer questions about disease spread in wild felids, with the aim of promoting conservation, and ultimately minimizing disease outbreaks in wildlife, domestic animals, and humans.

view project
research project

Feline Immunodeficiency Virus (FIV)

Cats infected with FIV, much like humans with HIV, suffer from oral disease. We are assessing how a novel combination antiretroviral therapy impacts infection, periodontal disease, and the cat's oral microbiome. This study is possible with the collaboration of microbiome experts, disease ecologists, veterinary dentists, veterinary immunologists and pathologists, and lab animal veterinarians.

research project

Microsporum Canis

M. canis is the primary pathogen in approximately 90% of Dermatophytosis cases in cats. Because the infection impacts the most adoptable (i.e. kittens), it can be a devastation in shelters. The infection can also be zoonotic and infects people worldwide. Our lab is currently investigating potential virulence genes in M. canis and developing a rapid point-of-care diagnostic for this agent.

research project

Diagnostics

The VandeWoude lab focuses on an array of pathogen testing through a variety of assays including conventional PCR, qPCR, ELISA, and multiplex bead based immunoassay. Current pathogens in our screening portfolio is feline foamy virus, feline gammaherpesvirus, feline immunodeficiency virus, puma and bobcat lentivirus, feline panleukopenia virus, and feline leukemia virus.

Publications

Detection of glucosamine as a marker for Aspergillus niger: a potential screening method for fungal infections.

Allison CL, Moskaluk A, VandeWoude S, Reynolds MM.
Anal Bioanal Chem. 2021 Feb 22. doi: 10.1007/s00216-021-03225-7. Online ahead of print.PMID: 33615396

Quantifying Proximity, Confinement, and Interventions in Disease Outbreaks: A Decision Support Framework for Air-Transported Pathogens.

Bond TC, Bosco-Lauth A, Farmer DK, Francisco PW, Pierce JR, Fedak KM, Ham JM, Jathar SH, VandeWoude S.
Environ Sci Technol. 2021 Mar 2;55(5):2890-2898. doi: 10.1021/acs.est.0c07721. Epub 2021 Feb 19.PMID: 33605140

Parasites as conservation tools.

Gagne RB, Crooks K, Craft ME, Chiu ES, Fountain-Jones NM, Malmberg JL, Carver S, Funk WC, VandeWoude S.
Conserv Biol. 2021 Feb 14. doi: 10.1111/cobi.13719. Online ahead of print.PMID: 33586245

Bioaccumulation of Pathogen Exposure in Top Predators.

Malmberg JL, White LA, VandeWoude S.
Trends Ecol Evol. 2021 Feb 3:S0169-5347(21)00024-0. doi: 10.1016/j.tree.2021.01.008. Online ahead of print.PMID: 33549372

Host relatedness and landscape connectivity shape pathogen spread in the puma, a large secretive carnivore.

Fountain-Jones NM, Kraberger S, Gagne RB, Trumbo DR, Salerno PE, Chris Funk W, Crooks K, Biek R, Alldredge M, Logan K, Baele G, Dellicour S, Ernest HB, VandeWoude S, Carver S, Craft ME.
Commun Biol. 2021 Jan 4;4(1):12. doi: 10.1038/s42003-020-01548-2.PMID: 33398025

more publications
57 students mentored at the undergraduate and graduate levels
>114 manuscripts published in scientific journals since 2000
69 grants and awards totaling in over $24 million worth of funding

People

Sue VandeWoude, D.V.M.

Lab Principal Investigator [PI]
University Distinguished Professor
Director, One Health Institute at Colorado State University

Mary Nehring

Research Associate III/Lab Manager

Elisa Behzadi, M.S.

Research Associate I

Andy Aghaian, D.V.M.

Postdoctoral Fellow

Alex Moskaluk, D.V.M.

Postdoctoral Fellow

Jeffrey Kim, D.V.M.

Postdoctoral Fellow

Laura Bashor

Graduate Research Assistant

Elliott Chiu, Ph.D.

Graduate Research Assistant

Megan Conry

Veterinarian Summer Student

Sam Hilty

MPH Student Researcher

Cassidy Stone

DVM Student Researcher

Raegan Petch

Student Researcher

news and updates view all