The VandeWoude Laboratory studies a variety of agents that infect domestic and nondomestic cats, most predominantly Feline Immunodeficiency Virus.
The mission of the VandeWoude Lab is to:
- Train undergraduate, graduate, pre- and post-DVM students, and post-doctoral fellows in modern techniques in molecular virology, with emphasis on experimental design, data interpretation, and accurate and fluent reporting of results.
- Strive to continuously develop new methodologies to apply to the research process.
- Facilitate productive and collaborative interactions between SVRG lab members and collaborators both internal and external to CSU.
- Extrapolate findings to whole animal and population health, in vivo relevance, and community/ecological impacts.
- Challenge existing dogma with an open mind and thoughtful approach.
- Generate enthusiasm and appreciation for the impact of well-considered scientific approaches on human and animal health and well-being.
- Provide a supportive, lively, challenging, cooperative and fun environment for scientific investigations in complementary disciplines.
Feline Ecology: Landscapes, Infectious Disease, And Epidemics
There are many questions about the spread of disease in felines. The FELIDAE (Feline Ecology: Landscapes, Infectious Disease, And Epidemics) research project seeks to answer questions about disease spread in wild felids, with the aim of promoting conservation, and ultimately minimizing disease outbreaks in wildlife, domestic animals, and humans.view project
Feline Immunodeficiency Virus (FIV)
Cats infected with FIV, much like humans with HIV, suffer from oral disease. We are assessing how a novel combination antiretroviral therapy impacts infection, periodontal disease, and the cat's oral microbiome. This study is possible with the collaboration of microbiome experts, disease ecologists, veterinary dentists, veterinary immunologists and pathologists, and lab animal veterinarians.
M. canis is the primary pathogen in approximately 90% of Dermatophytosis cases in cats. Because the infection impacts the most adoptable (i.e. kittens), it can be a devastation in shelters. The infection can also be zoonotic and infects people worldwide. Our lab is currently investigating potential virulence genes in M. canis and developing a rapid point-of-care diagnostic for this agent.
The VandeWoude lab focuses on an array of pathogen testing through a variety of assays including conventional PCR, qPCR, ELISA, and multiplex bead based immunoassay. Current pathogens in our screening portfolio is feline foamy virus, feline gammaherpesvirus, feline immunodeficiency virus, puma and bobcat lentivirus, feline panleukopenia virus, and feline leukemia virus.
Detection of glucosamine as a marker for Aspergillus niger: a potential screening method for fungal infections.
Anal Bioanal Chem. 2021 Feb 22. doi: 10.1007/s00216-021-03225-7. Online ahead of print.PMID: 33615396
Quantifying Proximity, Confinement, and Interventions in Disease Outbreaks: A Decision Support Framework for Air-Transported Pathogens.
Environ Sci Technol. 2021 Mar 2;55(5):2890-2898. doi: 10.1021/acs.est.0c07721. Epub 2021 Feb 19.PMID: 33605140
Conserv Biol. 2021 Feb 14. doi: 10.1111/cobi.13719. Online ahead of print.PMID: 33586245
Trends Ecol Evol. 2021 Feb 3:S0169-5347(21)00024-0. doi: 10.1016/j.tree.2021.01.008. Online ahead of print.PMID: 33549372
Host relatedness and landscape connectivity shape pathogen spread in the puma, a large secretive carnivore.
Commun Biol. 2021 Jan 4;4(1):12. doi: 10.1038/s42003-020-01548-2.PMID: 33398025
Lab Principal Investigator [PI]
University Distinguished Professor
Director, One Health Institute at Colorado State University
Research Associate III/Lab Manager
Research Associate I
Graduate Research Assistant
Graduate Research Assistant
Veterinarian Summer Student
MPH Student Researcher
DVM Student Researcher
news and updates
On International Women’s Day, we celebrate the contributions and impact from women everywhere, including all of the CSU scientists and researchers who have led in the fight against COVID-19
A COVID-19 Innovation Boettcher Foundation award to Sue VandeWoude is supporting the RESTARtT (Rational Effective Surveillance Testing Accelerating Return to Tasks) project.
She was immersed in One Health research. Our One Health Crisis intervened.
Offices: Pathology room 211A & 228
Laboratory: Pathology room 207