The Zabel Laboratory, as part of the CSU Prion Research Center, employs molecular biological, immunological, and biochemical techniques to explore peripheral pathogenesis and vaccines for prion diseases. Studying basic mechanisms of prion infection and dissemination provides translational information leading to vaccine targets and early disease detection. Dr. Zabel’s research program focuses on the interaction of prions with cells and receptors of the immune system and lymphoid tissues in the early entry, trafficking, and pathogenesis phases of prion infections. He utilizes novel mouse models of chronic wasting disease that have led to numerous publications detailing translational knowledge about the role of the complement system in prion replication, disease progression, and transmission.
People
Lab Pricipal Investigator
Associate Dean for Research, College of Veterinary Medicine & Biomedical Sciences
Professor
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Luke Davis, a Zabel and Wilusz Labs student researcher, wins the Spring 2023 Outstanding Grad Award for his invaluable contributions to campus saliva screenings and wastewater testing.
Top Colorado State University researchers mobilized their disciplines over the course of the past year to address challenges raised by the global coronavirus pandemic.
Infectious disease scientists across Colorado State University are focused on fighting the COVID-19 pandemic.
contact information
Office: Pathology room 227
Lab: Pathology room 218
(970) 491-1455
Mark.Zabel@colostate.edu