Ryan Lab – Faculty Research – College of Veterinary Medicine and Biomedical Sciences

Elizabeth Ryan
Toxicology, Cancer Biology and Nutrition Laboratory

This multi-disciplinary lab studies gut mucosal immunity and enteric pathogens, probiotic metabolism of food, nutrient digestibility and weight loss in companion animals, and gut microbial-metabolic health outcomes in colorectal cancer survivors and people at high risk for cancer. Laboratory studies and clinical trials are conducted throughout the lifespan of animal models and trial participants. This work informs translational research with applications for animal and human health. The lab also collaborates with local, national, and international groups on functional and sustainable food projects.

research project

Research Study: Northern Colorado Coronavirus Biobank

NoCo-Co-BIO: A biorepository for acute and convalescent patient samples from Coloradoans infected with SARS CoV-2.

research project

Clinical Research Study: Beans/Bran Enriching Nutritional Eating For Intestinal Health and Cancer Including Activity for Longevity

Beans/Bran Enriching Nutritional Eating For Intestinal Health and Cancer Including Activity for Longevity (BENEFICIAL) is a human clinical research study designed to identify whether foods such as beans or rice bran, combined with regular physical activity, can lower the risk of colorectal cancer.

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Publications

Metabolite profile comparisons between ascending and descending colon tissue in healthy adults

Bridget A. Baxter, Kristopher D. Parker, Michael J Nosler, Sangeeta Rao, Rebecca Craig, Catherine Seiler and Elizabeth P. Ryan
World Journal of Gastroenterology (2020)

Non-Targeted Metabolomics Signature in the Plasma and Bone Marrow of Patients with Long Bone Injuries

Hend Ibrahim, Omar Alnachoukati, Bridget A. Baxter, Trinette Chapin, Thomas Schroeppel, Julie Dunn and Elizabeth P. Ryan
Current Metabolomics and Systems Biology (2019)

Bifidobacterium longum-fermented rice bran and rice bran supplementation affects the gut microbiome and metabolome

Nora Jean Nealon, Kristopher D. Parker, Hend Ibrahim, Akhilendra Maurya, Kamol Raina and Elizabeth P. Ryan
Beneficial Microbes (2019)

Modulation of plasma and urine metabolome in colorectal cancer survivors consuming rice bran

Iman Zarei, Renee C. Oppel, Erica C. Borresen, Regina J. Brown, and Elizabeth P. Ryan
Integrating Food, Nutrition and Metabolism (2019)

Rice bran supplementation modulates growth, microbiota and metabolome in weaning infants: a clinical trial in Nicaragua and Mali

Luis E. Zambrana, Starin McKeen, Hend Ibrahim, Iman Zarei, Erica C. Borresen, Lassina Doumbia, Abdoulay Bore, Alima Cissolo, Seydou Douyon, Karim Kone, Johann Perez, Claudia Perez, Ann Hess, Zaid Abodo, Lansana Sangara, Ababacar Maiga, Syliva Becker-Dreps, Lijuan Yuan, Ousmane Koita, Samuel Vilchez, and Elizabeth P. Ryan
Scientific Reports (2019)

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